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Hormone Therapy, also known as Androgen Deprivation Therapy (ADT) is generally used in the treatment of
advanced Prostate Cancer, (cancer which has spread beyond the prostate) but can also be used in association with external beam radiotherapy and in patients undergoing low dose rate brachytherapy to help shrink the size of the prostate.
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ADT has many uses. It can be used in men with advanced disease, where the cancer has spread from the confines of the prostate to other parts of the body. In this situation, it can immediately decrease pain from spread of prostate cancer to the bones and can delay the progression of the prostate cancer.
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Many normal cells also rely on testosterone to remain healthy. Side effects occur because the lack of testosterone affects normal cell function.
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Unfortunately prostate cancer may eventually stop responding to ADT and becomes hormone resistant. This is when the tumour no longer responds to the therapy and the prostate cancer cells carry on growing.
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